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Pui Seto Selected Research

Neoplasms (Cancer)

1/2022Regression of EGFR positive established solid tumors in mice with the conditionally active T cell engager TAK-186.
1/2021TriTACs, a Novel Class of T-Cell-Engaging Protein Constructs Designed for the Treatment of Solid Tumors.
1/2020COBRA™: a highly potent conditionally active T cell engager engineered for the treatment of solid tumors.
1/2010Antibodies to TWEAK receptor inhibit human tumor growth through dual mechanisms.
11/2007A function blocking anti-mouse integrin alpha5beta1 antibody inhibits angiogenesis and impedes tumor growth in vivo.

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Pui Seto Research Topics

Disease

5Neoplasms (Cancer)
01/2022 - 11/2007
1Prostatic Neoplasms (Prostate Cancer)
01/2021
1Schizophrenia (Dementia Praecox)
05/2013
1Mental Disorders (Mental Disorder)
05/2013
1Cardiovascular Diseases (Cardiovascular Disease)
05/2013
1Dystonia (Limb Dystonia)
05/2013
1Parkinson Disease (Parkinson's Disease)
05/2013
1Mood Disorders (Mood Disorder)
05/2013
1Inflammation (Inflammations)
01/2012
1Renal Cell Carcinoma (Grawitz Tumor)
11/2007
1Carcinoma (Carcinomatosis)
11/2007
1Melanoma (Melanoma, Malignant)
11/2007

Drug/Important Bio-Agent (IBA)

2AntigensIBA
01/2022 - 01/2020
2Surface Antigens (Surface Antigen)IBA
01/2022 - 01/2021
2T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2021 - 01/2020
2Proteins (Proteins, Gene)FDA Link
01/2021 - 05/2013
1ProdrugsIBA
01/2022
1bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA
01/2021
1Matrix Metalloproteinases (MMPs)IBA
01/2020
1Serum AlbuminIBA
01/2020
1BuffersIBA
05/2013
1CatecholaminesIBA
05/2013
1Dopamine (Intropin)FDA LinkGeneric
05/2013
1EnzymesIBA
05/2013
1ImmunosorbentsIBA
05/2013
1Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
05/2013
1SynucleinsIBA
05/2013
1Laminin (Merosin)IBA
01/2012
1AntibodiesIBA
01/2010
1LigandsIBA
01/2010
1TWEAK ReceptorIBA
01/2010
1enavatuzumabIBA
01/2010
1Monoclonal AntibodiesIBA
01/2010
1Immunoglobulin G (IgG)IBA
01/2010
1Complementary DNA (cDNA)IBA
01/2010
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2007
1volociximabIBA
11/2007
1IntegrinsIBA
11/2007
1Integrin alpha5beta1IBA
11/2007

Therapy/Procedure

2Therapeutics
01/2021 - 01/2010
1Castration
01/2021